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Related Concept Videos

Role of Shaping in Operant Conditioning01:19

Role of Shaping in Operant Conditioning

Shaping is a technique used in operant conditioning to train complex behaviors by rewarding successive approximations toward the target behavior. This method is necessary because organisms are unlikely to perform complex behaviors spontaneously. Instead, shaping breaks down the desired behavior into small, manageable steps.
The steps involved in shaping begin with reinforcing any response that resembles the desired behavior. For example, parents might praise a child for picking up one toy. As...
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Modeling in Therapy

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Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in situations...
Autism Spectrum Disorder01:19

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
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Three Developmental Domains01:29

Three Developmental Domains

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Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
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Stella Chess...
Operant Conditioning Intervention01:24

Operant Conditioning Intervention

Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...

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Related Experiment Video

Updated: May 26, 2026

A Treatment Package without Escape Extinction to Address Food Selectivity
04:23

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Published on: August 21, 2015

Shaping development with ESCRTs.

Tor Erik Rusten1, Thomas Vaccari, Harald Stenmark

  • 1Centre for Cancer Biomedicine, Oslo University Hospital, Montebello, 0310 Oslo, Norway.

Nature Cell Biology
|December 24, 2011
PubMed
Summary
This summary is machine-generated.

Endosomal sorting complexes required for transport (ESCRT) proteins, initially known for endosomal sorting, are now recognized for diverse roles in cell functions and development. These evolutionarily conserved proteins significantly impact cellular processes and organismal development.

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Area of Science:

  • Cell Biology
  • Molecular Biology
  • Developmental Biology

Background:

  • Endosomal sorting complexes required for transport (ESCRT) were initially identified for their roles in endosomal sorting and multivesicular endosome (MVE) biogenesis.
  • ESCRT proteins are crucial for regulating the trafficking of ubiquitinated membrane proteins.

Purpose of the Study:

  • To explore the expanded functions of ESCRT proteins beyond their canonical roles in endosomal sorting.
  • To understand the pleiotropic effects of ESCRT proteins on various cellular processes and developmental trajectories.

Main Methods:

  • Literature review and synthesis of existing research on ESCRT protein functions.
  • Analysis of studies investigating ESCRT involvement in diverse cellular pathways.

Main Results:

  • ESCRT components regulate a wide array of cellular functions including receptor signaling, cytokinesis, autophagy, cell polarity, migration, miRNA activity, and mRNA transport.
  • The diverse functions of ESCRT proteins contribute to a broad spectrum of developmental outcomes.

Conclusions:

  • ESCRT proteins are versatile molecular machines with critical roles in fundamental cellular processes.
  • The pleiotropic nature of ESCRT functions underscores their evolutionary conservation and importance in development.