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Perioperative blood glucose level and postoperative complications in pediatric cardiac surgery
Rodrigo Leal Alves1, Macius Pontes Cerqueira, Nadja Cecília de Castro Kraychete
1Hospital São Rafael, Salvador, BA, Brazil. peres@mail.com
Insights
Elevated intraoperative blood glucose levels in children undergoing cardiac surgery are linked to increased postoperative complications. Monitoring blood glucose is crucial for predicting morbidity in these critically ill pediatric patients.
Area of Science:
- Pediatric Anesthesiology
- Cardiovascular Surgery
- Metabolic Response to Trauma
Background:
- Pediatric cardiac surgery patients are critically ill with physiological instability.
- Intraoperative factors like temperature and inflammation impact patient outcomes.
- Blood glucose monitoring can predict morbidity in this population.
Purpose of the Study:
- To correlate perioperative blood glucose levels with postoperative complications in pediatric cardiac surgery.
- To compare intraoperative blood glucose levels based on perioperative conditions.
Main Methods:
- Retrospective review of medical records for surgical/anesthetic procedures and perioperative conditions.
- Comparison of mean perioperative blood glucose levels between patients with and without complications using statistical analyses.
- Odds ratio and non-parametric univariate analyses were employed.
Main Results:
- Higher intraoperative blood glucose levels were associated with postoperative complications.
- Extracorporeal circulation (ECC) correlated with elevated intraoperative blood glucose.
- Specific complications (infectious, cardiovascular, hematological) were linked to higher glucose levels depending on ECC use.
Conclusions:
- Elevated intraoperative blood glucose is a significant predictor of increased morbidity after pediatric cardiac surgery.
- Blood glucose levels serve as a prognostic marker for adverse outcomes.
Background:
Anesthesia for pediatric cardiac surgery is systematically performed in severely ill patients under abnormal physiological conditions. In the intraoperative period, there are significant variations in blood volume, body temperature, plasma composition, and tissue blood flow, in addition to activation of inflammation, with important consequences. Serial measurements of blood glucose levels can indicate states of exacerbation of the neuroendocrine-metabolic response to trauma, serving as prognostic markers of morbidity in that population.
Objective:
To correlate perioperative blood glucose levels of children undergoing cardiac surgery with the occurrence of postoperative complications, and to compare intraoperative blood glucose levels according to perioperative conditions.
Methods:
Information regarding the surgical/anesthetic procedure and perioperative conditions of patients was collected from the medical records. The mean perioperative blood glucose levels in the groups of patients with and without postoperative complications and the frequencies of perioperative conditions were compared by use of odds ratio and non-parametric univariate analyses.
Results:
Higher intraoperative blood glucose levels were observed in individuals who had postoperative complications. Prematurity, age group, type of anesthesia, and character of the procedure did not influence the mean intraoperative blood glucose level. The use of extracorporeal circulation (ECC) was associated with higher blood glucose levels during surgery. In procedures with ECC, higher blood glucose levels were observed in individuals who had infectious and cardiovascular complications. In surgeries without ECC, that association was observed with infectious and hematological complications.
Conclusion:
Higher intraoperative blood glucose levels are associated with higher morbidity in the postoperative period of pediatric cardiac surgery.
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