Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

40.1K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.1K
Bone Structure01:55

Bone Structure

51.3K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
51.3K
Compact Bone01:27

Compact Bone

15.7K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
15.7K
The Bone Matrix01:18

The Bone Matrix

5.3K
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
5.3K
Spongy Bone01:09

Spongy Bone

7.3K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
7.3K
Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

6.2K
Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
6.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pioneers and paradigms in sprint science: a thematic historical mini review.

Frontiers in sports and active living·2026
Same author

Choice of anesthesia in microelectrode recording-guided deep brain stimulation surgery for Parkinson's disease (CHAMPION): A noninferiority randomized controlled trial.

Anesthesiology·2026
Same author

Fungal small RNA: unveiling the breakthroughs and promising applications.

Frontiers in fungal biology·2026
Same author

Explicit dynamics analysis of forearm tendon stresses during the forehand smash.

Frontiers in bioengineering and biotechnology·2026
Same author

Laryngotracheal Anastomosis for Cervical Upper Digestive Tract Reconstruction Following Hypopharyngeal Cancer Resection: A Case Report.

Ear, nose, & throat journal·2026
Same author

Robotic-assisted optical navigation system for CT-guided preoperative percutaneous Hook-wire localization of pulmonary nodules: a prospective, single-center, single-arm clinical study.

World journal of surgical oncology·2026
Same journal

Analysis of strength degradation of coal and rock masses and stability of mined areas under long term immersion environment.

PloS one·2026
Same journal

Biogenic Silver-Selenium nanocomposite with anticancer activity and potent efficacy against vancomycin-resistant Staphylococcus aureus.

PloS one·2026
Same journal

Preparation and physicochemical characterization of a biodegradable chitosan/carboxymethyl cellulose hydrogel synthesized in NaOH/urea medium.

PloS one·2026
Same journal

Action-guilt, survivor-guilt, and depression in combat-related PTSD.

PloS one·2026
Same journal

Explainable machine learning for predicting activities of daily living at discharge in stroke patients: A retrospective study using SHAP interpretability.

PloS one·2026
Same journal

Deep learning based two-way feature depiction model for brain tumor detection.

PloS one·2026
See all related articles

Related Experiment Video

Updated: Dec 23, 2025

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

3.2K

Optimal principle of bone structure.

Yifang Fan1, Yubo Fan, Zhiyu Li

  • 1Center for Scientific Research, Guangzhou Institute of Physical Education, Guangzhou, People's Republic of China. tfyf@gipe.edu.cn

Plos One
|December 24, 2011
PubMed
Summary
This summary is machine-generated.

Researchers found that bone

More Related Videos

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests
04:20

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Published on: September 1, 2023

1.2K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

10.0K

Related Experiment Videos

Last Updated: Dec 23, 2025

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

3.2K
Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests
04:20

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Published on: September 1, 2023

1.2K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

10.0K

Area of Science:

  • Biomechanical Engineering
  • Orthopedic Research
  • Materials Science

Background:

  • Bone modeling and remodeling lack a unified theoretical model.
  • Understanding these processes is crucial for treating bone diseases and injuries.

Purpose of the Study:

  • To investigate the relationship between the center of mass and centroid of shape in bone.
  • To propose new indices for evaluating bone strength based on these relationships.

Main Methods:

  • In vivo measurement of 384 bone samples using 64-slice CT scans.
  • Analysis of the superposition of the center of mass and centroid of shape.
  • Development of novel indices relating center of mass, centroid of shape, tissue density, and distribution radius.

Main Results:

  • The center of mass and centroid of shape were found to approximately superpose in bone.
  • This suggests bone follows superposition laws similar to homogeneous materials.
  • New indices were developed to assess compact bone properties and strength.

Conclusions:

  • The superposition principle offers a new perspective on bone optimization processes.
  • The proposed indices provide a novel method for evaluating bone strength.
  • Further research can refine these indices for clinical applications in bone health.