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Related Concept Videos

Lipid Absorption01:24

Lipid Absorption

Dietary triglycerides from chyme in the duodenum are mixed with bile salts produced by the liver to emulsify fats. As a result, large droplets are broken down into smaller ones, increasing the surface area for enzymatic action. Once emulsified, pancreatic lipases hydrolyze the triglycerides into free fatty acids and monoglycerides.
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Lipid-derived Compounds in the Human Body

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Overview of Lipid Metabolism

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Related Experiment Video

Updated: May 26, 2026

Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

TB lipidomics--the final frontier.

Eric D Chow1, Jeffery S Cox

  • 1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.

Chemistry & Biology
|December 27, 2011
PubMed
Summary
This summary is machine-generated.

Mycobacterium tuberculosis lipidomics is advanced by a new technique and database. This systems-level approach aids understanding of critical lipids in this human pathogen.

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Shotgun Lipidomics of Rodent Tissues
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Published on: November 18, 2022

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Lipidomics and Transcriptomics in Neurological Diseases
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Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

Area of Science:

  • Microbiology
  • Biochemistry
  • Systems Biology

Background:

  • Lipids are crucial for Mycobacterium tuberculosis pathogenesis, yet systems-level lipid analysis has lagged.
  • Existing "omics" approaches have not fully addressed the complexity of mycobacterial lipids.

Discussion:

  • Layre et al. present a novel, powerful lipidomics technique for comprehensive analysis.
  • This technique enables the creation of a detailed lipid database for Mycobacterium tuberculosis.

Key Insights:

  • The developed method significantly enhances the study of mycobacterial lipids.
  • A comprehensive database provides a valuable resource for researchers.

Outlook:

  • This work paves the way for deeper understanding of lipid roles in tuberculosis.
  • Future research can leverage these tools for drug discovery and therapeutic strategies.