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Related Concept Videos

Degenerative Disc Disease ll: Pathophysiology01:23

Degenerative Disc Disease ll: Pathophysiology

The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

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C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position
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Multi-level spondylolysis.

David S Hersh1, Yong H Kim, Afshin Razi

  • 1Department of Neurosurgery, University of Maryland Medical Center, Baltimore, Maryland, USA.

Bulletin of the NYU Hospital for Joint Diseases
|December 27, 2011
PubMed
Summary
This summary is machine-generated.

Multi-level spondylolysis, a rare spinal condition, was treated using a novel combination of direct pars defect repair and interbody fusion. This case study demonstrates successful clinical improvement in a patient with bilateral defects at L3-L5.

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Area of Science:

  • Spine surgery
  • Orthopedics
  • Neurosurgery

Background:

  • Isthmic spondylolysis affects 3-6% of the population, but multi-level defects are exceptionally rare.
  • Surgical outcomes for multi-level spondylolysis are sparsely reported in existing literature.

Observation:

  • A 46-year-old female presented with low back pain and left leg radiation.
  • Imaging revealed bilateral pars defects at L3, L4, and L5 (lumbar spine).

Findings:

  • The patient underwent a combined surgical approach: direct pars defect repair at L3 and L4-S1 interbody fusion.
  • No postoperative complications were noted.
  • Significant clinical improvement was observed by seven months post-surgery.

Implications:

  • This case highlights the potential efficacy of combining direct pars repair and interbody fusion for multi-level spondylolysis.
  • This combined technique may offer a viable treatment option for rare, complex spondylolysis cases.
  • Further research is warranted to evaluate the long-term outcomes of this combined surgical strategy.