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Aortic valve calcium score as a predictor for outcome after TAVI using the CoreValve revalving system

Alexander W Leber1, Markus Kasel, Thomas Ischinger

  • 1Department of Cardiology, Heart Center Bogenhausen, Klinikum München Bogenhausen, Technical University of Munich, Germany. leber@heart-center-muc.de

International Journal of Cardiology
|December 27, 2011
PubMed

Insights

The aortic valve calcification score, determined via CT scans, accurately predicts outcomes after transcatheter aortic valve implantation (TAVI). This score helps assess risks, complications, and functional improvement post-TAVI.

Area of Science:

  • Cardiology
  • Radiology
  • Medical Imaging

Background:

  • Transcatheter aortic valve implantation (TAVI) is a key treatment for high-risk surgical patients.
  • Existing surgical risk scores inadequately predict TAVI outcomes.
  • There is a need for alternative risk stratification parameters in TAVI.

Purpose of the Study:

  • To assess the predictive value of CT-derived aortic valve calcification score for TAVI outcomes.
  • To determine if aortic valve calcification can identify patients at higher risk for complications and mortality.
  • To explore the association between calcification score and functional improvement after TAVI.

Main Methods:

  • 68 patients undergoing transfemoral TAVI with the CoreValve device were analyzed.
  • Aortic valve calcium scoring was performed using preprocedural 64-slice ECG-gated CT scans.
  • Statistical analysis included linear regression to identify predictors of outcomes.

Main Results:

  • The aortic valve calcium score significantly predicted 30-day Major Adverse Cardiovascular Events (MACE) and 1-year mortality.
  • Higher calcium scores (>750) correlated with significantly lower 1-year survival rates (58% vs. 98%).
  • The score was associated with post-procedural aortic regurgitation and inversely with NYHA-class improvement.

Conclusions:

  • Aortic valve calcification degree predicts TAVI complications, mortality, and functional recovery.
  • CT-derived aortic valve calcium scoring is a valuable tool for risk stratification and patient selection in TAVI.
  • This parameter can be integrated into pre-procedural planning using existing CT data.
Abstract

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