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Related Concept Videos

Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...

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Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
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Published on: November 21, 2013

Short self-assembling peptides as building blocks for modern nanodevices.

Anupama Lakshmanan1, Shuguang Zhang, Charlotte A E Hauser

  • 1Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669.

Trends in Biotechnology
|December 27, 2011
PubMed
Summary

Short peptides self-assemble into nanostructures for advanced bionanotechnology. These versatile building blocks enable the rational design of functional electronic, photonic, and plasmonic devices.

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Area of Science:

  • Bionanotechnology
  • Materials Science
  • Nanotechnology

Background:

  • Short peptides self-assemble into stable nanostructures.
  • Peptides act as organic templates for creating ordered nanoparticle arrays and hybrid supramolecular structures.
  • Bionanotechnology is advancing towards electronic, photonic, and plasmonic applications.

Purpose of the Study:

  • To review the emerging role of short, linear self-assembling peptides.
  • To highlight their use as versatile building blocks for nanodevices.
  • To discuss recent advances and applications in bionanotechnology.

Main Methods:

  • Review of recent literature on peptide self-assembly.
  • Analysis of methods for controlling and manipulating nanostructures.
  • Examination of nanostructure properties like piezoelectricity and stability.

Main Results:

  • Self-assembly of peptides yields functional nanostructures for devices.
  • Advances include photoluminescent semiconducting nanowires and peptide-conjugated systems.
  • Growing knowledge on nanostructure properties enhances their application potential.

Conclusions:

  • Short, self-assembling peptides are simple and versatile building blocks for nanodevices.
  • These peptides are crucial for the rational design of functional bionanotechnology applications.
  • The field is rapidly evolving with new methods and applications.