[Paraneoplastic psychopathologic syndromes]

The diagnosis of paraneoplastic neuro-psychic syndromes is very difficult and still remains an unresolved issue. A retrospective analysis included case histories of 79 patients with marked psychopathologic symptoms concomitant to cancer which had been verified at autopsy but had been difficult to diagnose during life. All these cases are regarded as having suffered paraneoplastic psychopathologic syndromes which are of great clinical and diagnostic interest. Certain theoretical observations concerning the pathogenetic mechanisms underlying paraneoplastic psychic disorders are made.