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Selenium. Nutritional, toxicologic, and clinical aspects.

A M Fan1, K W Kizer

  • 1Pesticide, Food, and Water Toxicology Unit, California Department of Health Services, Berkeley 94704.

The Western Journal of Medicine
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

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Selenium toxicosis is rare in the US, even with environmental contamination. Diverse diets prevent chronic selenosis, but medical professionals need awareness due to supplement interest and contamination risks.

Area of Science:

  • Environmental Science
  • Toxicology
  • Human Nutrition

Background:

  • Recent findings indicate environmental selenium contamination.
  • Human selenium toxicosis is rare in the United States.
  • Known cases stem from industrial accidents or excessive supplement intake.

Purpose of the Study:

  • To review the nutritional, toxicologic, and clinical aspects of selenium.
  • To inform medical practitioners about selenium's risks and benefits.
  • To address growing public interest in selenium supplements.

Main Methods:

  • Literature review on selenium's role in human health and toxicity.
  • Analysis of reported cases of selenium toxicosis in the US.
  • Examination of dietary selenium intake and environmental contamination levels.

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Main Results:

  • Chronic selenosis is uncommon in the US due to dietary diversity.
  • Acute selenium toxicity is linked to specific incidents, not general dietary exposure.
  • Environmental selenium contamination and supplement use are increasing concerns.

Conclusions:

  • Medical practitioners require updated knowledge on selenium's dual role (nutrient and toxin).
  • Public interest in selenium supplements necessitates awareness of potential toxicity.
  • Understanding selenium's clinical and toxicologic profile is crucial for public health.