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Updated: May 26, 2026

Intracellular Recording, Sensory Field Mapping, and Culturing Identified Neurons in the Leech, Hirudo medicinalis
Published on: November 4, 2013
[Medicinal leeches and hirudotherapy].
Ahmet Gödekmerdan1, Suat Arusan, Batu Bayar
1Fırat Üniversitesi Tıp Fakültesi, İmmünoloji Anabilim Dalı, Elazığ, Türkiye. agodekmerdan@hotmail.com
Medicinal leeches, abundant in Turkey, secrete over 100 bioactive compounds. Hirudotherapy, or leech therapy, offers significant therapeutic benefits for various medical conditions.
Area of Science:
- Biomedical Science
- Zoology
- Pharmacology
Background:
- Leeches have a long history of medicinal use.
- Turkey is a major global exporter of medicinal leeches, particularly Hirudo medicinalis and Hirudo verbana.
- Leech secretions contain over 100 bioactive substances with diverse therapeutic properties.
Purpose of the Study:
- To highlight the therapeutic potential of medicinal leeches.
- To emphasize Turkey's significant role in the global supply of leeches.
- To advocate for the expanded use of hirudotherapy in modern medicine.
Main Methods:
- Review of historical and current applications of medicinal leeches.
- Analysis of the biochemical composition of leech salivary gland secretions.
- Examination of regulatory approvals for leech therapy, such as by the U.S. Food and Drug Administration (FDA).
Main Results:
- Leech secretions possess vasodilatory, bacteriostatic, analgesic, anti-inflammatory, and anticoagulant properties.
- These secretions can resolve microcirculatory disorders, restore vascular permeability, alleviate hypoxia, and reduce blood pressure.
- Hirudotherapy can enhance immune activity, relieve pain, and improve the body's bioenergetic status.
Conclusions:
- Medicinal leeches represent a valuable natural resource, especially in Turkey.
- Hirudotherapy holds significant potential as a supportive treatment in contemporary medical practices.
- Further research and application of hirudotherapy are crucial for leveraging its full benefits.
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