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Updated: May 26, 2026
06:46
Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
1-(4-Benz-yloxy-2-hy-droxy-phen-yl)ethanone
Acta Crystallographica. Section E, Structure Reports Online
|December 27, 2011
Summary
Researchers synthesized a novel compound, C(15)H(14)O(3), using 2,4-dihydroxyacetophenone. The study details its unique intramolecular hydrogen bonding and intermolecular crystal contacts.
Area of Science:
- Organic Chemistry
- Crystallography
Background:
- Synthesis of novel organic compounds is crucial for materials science and drug discovery.
- Understanding molecular interactions, such as hydrogen bonding, is key to predicting material properties.
Purpose of the Study:
- To synthesize and characterize a new organic compound.
- To investigate the structural features, including hydrogen bonding and crystal packing, of the synthesized compound.
Main Methods:
- Chemical synthesis involving 2,4-dihydroxyacetophenone, potassium carbonate, and benzyl bromide.
- Crystallographic analysis to determine the compound's structure and intermolecular interactions.
Main Results:
- Successful synthesis of the title compound, C(15)H(14)O(3).
- Identification of an intramolecular O-H⋯O hydrogen bond involving the remaining hydroxy group.
- Observation of intermolecular C-H⋯O contacts in the crystal structure.
Conclusions:
- The synthesized compound exhibits specific intramolecular hydrogen bonding.
- The crystal structure reveals intermolecular C-H⋯O contacts, contributing to the overall molecular arrangement.
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