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Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
6-Fluoro-2-(4-meth-oxy-phen-yl)imidazo[2,1-b][1,3]benzothia-zole
Abstract:
The asymmetric unit of the title compound, C(16)H(11)FN(2)OS, comprises two independent mol-ecules in which the benzothia-zole rings are essentially planar, with maximum deviations of 0.038 (2) and 0.045 (3) Å. The central benzothia-zole ring makes dihedral angles of 4.87 (13) and 0.64 (12)° and 4.04 (12) and 3.67 (12)° with the two terminal phenyl rings in the two independent mol-ecules. In the crystal, mol-ecules are connected via weak inter-molecular C-H⋯O hydrogen bonds forming supra-molecular chains along the c axis.
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