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Updated: May 26, 2026

Chemical Triphosphorylation of Oligonucleotides
Published on: June 2, 2022
4-(2,4-Dichloro-phen-yl)-5,5-dimethyl-2-(3-silatranyl-propyl-mino)-1,3,2-dioxa-phospho-rinane 2-oxide
Zhe-Rong Liu1, Xiao-Jing Tan, De-Jian Wang
1School of Chemical and Environmental Engineering, Hubei University for Nationalities, Enshi, Hubei 445000, Peoples' Republic of China.
Abstract:
In the title compound, C(20)H(31)Cl(2)N(2)O(6)PSi, the dioxaphospho-rinane ring adopts a cis conformation. The silatrane fragment forms a cage-like structure in which there exists an intra-molecular Si-N donor-acceptor bond. In the crystal, centrosymmetrically related mol-ecules are linked by pairs of N-H⋯O hydrogen bonds into inversion dimers, generating rings with graph-set motif R(2) (2)(8). The dimers are further connected into ribbons parallel to the a axis by inter-molecular C-H⋯O hydrogen bonds.
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