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Updated: May 26, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
Ethyl 4-[(E)-(2-hy-droxy-benzyl-idene)amino]-piperidine-1-carboxyl-ate
Abstract:
In the title compound, C(15)H(20)N(2)O(3), the piperidine ring adopts a chair conformation, although the amide N atom is almost planar (bond angle sum = 359.7°). The mol-ecule adopts an E conformation about the C=N bond, which allows for the formation of an intra-molecular O-H⋯N hydrogen bond. In the crystal, mol-ecules are linked by C-H⋯O inter-ations, resulting in C(6) chains propagating in [010].
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