[Anti-inflammatory effects of liposomes]

Studies of antiexudative, antialterative, and antibacterial effects of lecithin-cholesterol liposomes suggest their possible use as antiinflammatory agents. It is shown that incubation of liposomes with opportunistic microorganisms is attended with a pronounced antibacterial effect, while subcutaneous injection of liposomes significantly reduces the soft tissue edema caused by administration of formalin, and prevents pronounced alteration in response to acetic acid solution. A conclusion is derived on the possibility to use the membranotropic properties of liposomal membranes to alleviate manifestations of inflammation.