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Updated: May 26, 2026

Microhardness Measurements on Tooth and Alveolar Bone in Rodent Oral Disease Models
Published on: April 26, 2024
Scanning electron microscopic observation of morphological modifications produced by Fluorostom on enamel surface
Cristina Nicolae1, Mihaela Hîncu, C Amariei
1Faculty of Dental Medicine, Ovidius University, Constanta, Romania. dr.cristina_nicolae@yahoo.com
Unlabelled:
In this in vitro study, examination of the morphological changes of enamel surface after topical application of a sodium fluoride solution was performed. Validation of the Fluorostom effectiveness became possible, after 10 years of using for the caries prevention national program.
Materials And Methods:
Sound human enamel sections, ware treated with a 0.05% sodium fluoride solution. Demineralization areas were created with 37% phosphoric acid etching gel for 60 seconds. The demineralization areas were immersed in 100 mL of sodium fluoride solution, twice daily for 30 days. Surface examination was performed at scanning electron microscope and energy dispersion spectrometry.
Results:
Morphological appearance of fluoride deposits on the enamel surface revealed the presence of globular precipitates. EDX qualitative analysis revealed the presence of fluoride signals.
Conclusions:
Globular structures of amorphous CaF2 precipitates, which act as a fluoride reservoir, were observed on the enamel surface after action of Fluorostom, and it can be recommended to prevent and control tooth decay.
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