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Structure-based design in the GPCR target space

M Kontoyianni1, Z Liu

  • 1Department of Pharmaceutical Sciences, Southern Illinois University Edwardsville, Edwardsville, IL 62026, USA. mkontoy@siue.edu

Current Medicinal Chemistry
|December 30, 2011
PubMed
Summary

G protein-coupled receptors (GPCRs) are key drug targets. This review covers GPCR structures, activation states, and computational modeling, highlighting their continued importance in drug discovery.

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