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Related Experiment Videos

[Minor neurological signs in obsessive-compulsive disorders].

V Conde López1, J J de la Gándara Martín, M L Blanco Lozano

  • 1Departmental de Psicología Médica y Psiquiatría, Facultad de Medicina de Valladolid.

Actas Luso-Espanolas De Neurologia, Psiquiatria Y Ciencias Afines
|May 1, 1990
PubMed
Summary

Obsessive-compulsive disorder (OCD) is linked to soft neurologic signs (SNS), particularly in coordination and balance. These findings suggest neurobiological underpinnings rather than organic impairment in OCD etiology.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Neurology

Background:

  • Obsessive-compulsive disorder (OCD) is associated with various neurological anomalies, prompting research into its etiopathogenesis.
  • Soft neurologic signs (SNS) are subtle neurological abnormalities that may indicate underlying brain dysfunction.
  • Previous studies suggest a link between OCD and neurological findings, but further investigation is warranted.

Purpose of the Study:

  • To investigate the incidence and nature of soft neurologic signs (SNS) in patients with obsessive-compulsive disorder (OCD).
  • To compare SNS prevalence in OCD patients with those in phobic disorder patients and healthy controls.
  • To explore potential correlations between SNS and demographic, clinical, intellectual, and neuropsychological variables in OCD.

Main Methods:

Related Experiment Videos

  • A study involving 20 patients diagnosed with OCD (DSM-III), 28 patients with phobic disorders, and 20 healthy controls.
  • Assessment using a standardized soft neurologic signs (SNS) protocol.
  • Administration of intellectual efficiency exams (WAIS) and neuropsychological tests (Benton/Bender) in a blinded manner.

Main Results:

  • The OCD group exhibited a higher global incidence of SNS compared to controls, with notable alterations in upper extremity coordination and balance.
  • A trend towards more anomalies in dominance-laterality was observed in the OCD group.
  • SNS incidence in OCD did not correlate with age, psychiatric history, neuropsychological impairment, or pharmacotherapy, but showed a relationship with schooling, particularly in males.

Conclusions:

  • Patients with OCD demonstrate a higher prevalence of soft neurologic signs (SNS), especially concerning motor coordination and balance.
  • The findings suggest a potential neurobiological basis for OCD, aligning with neurobiological hypotheses.
  • The results do not support neuroevolutionary or generalized organic impairment theories as the primary cause of OCD etiopathogenesis.