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Updated: May 26, 2026

Isolation of Murine Embryonic Hemogenic Endothelial Cells
Published on: June 17, 2016
Endothelio-hematopoietic relationship: getting closer to the beginnings
Sabrina Gordon-Keylock1, Alexander Medvinsky
1Institute for Stem Cell Research, MRC Centre for Regenerative Medicine, 5 Little France Drive, Edinburgh EH16 4UU, Scotland, UK.
None:
The close association between hematopoietic and endothelial cells during embryonic development led to the proposal that they may originate from a common ancestor--the hemangioblast. Due to a lack of unique specific markers for in vivo cell fate tracking studies, evidence supporting this theory derives mainly from in vitro differentiation studies. Teixeira and colleagues describe a novel enhancer that drives specific eGFP expression in blood islands of the electroporated chick embryo, thereby presenting a tool potentially suitable for analysis of hemangioblast differentiation and development of blood islands.
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