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Changes in carotid artery compliance with age.
J J Baskett1, R R Lewis, M G Beasley
1Non Invasive Angiology Group, Guy's Hospital, London.
Age and Ageing
|July 1, 1990
Summary
Arterial compliance significantly decreases with age until 50 years. Women
Area of Science:
- Vascular biology
- Cardiovascular physiology
Background:
- Arterial compliance is a key indicator of vascular health.
- Age-related changes in arterial stiffness are well-documented.
Purpose of the Study:
- To non-invasively assess arterial compliance in carotid arteries.
- To investigate age and sex differences in arterial compliance.
Main Methods:
- Utilized Doppler-shifted ultrasound for non-invasive measurements.
- Recruited 270 males and 388 females aged 5-90 years.
- Measured compliance in internal and external carotid arteries.
Main Results:
- Significant decrease in arterial compliance from age 5 to 50 (p < 0.001).
- Compliance plateaued after age 50.
- Women exhibited higher arterial compliance than men between ages 35-60.
Conclusions:
- Arterial compliance declines significantly during early to middle adulthood.
- Sex-based differences in arterial compliance emerge during mid-adulthood.