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Updated: May 26, 2026
06:35
Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
B-cell lymphoma presenting as acute pancreatitis
Edda Federico1, Massimo Falconi, Gianni Zuodar
1Department of Internal Medicine, University Hospital of Udine, Udine, Italy.
Summary
This case report details a rare instance of diffuse large B-cell lymphoma affecting both the pancreas and lungs simultaneously, presenting initially as acute pancreatitis. Early diagnosis and chemotherapy were crucial for managing this uncommon presentation of non-Hodgkin's lymphoma.
Area of Science:
- Oncology
- Gastroenterology
- Pulmonology
Background:
- Pancreatic lymphoma is a rare malignancy, accounting for less than 0.5% of pancreatic tumors.
- Diffuse large B-cell lymphoma (DLBCL) is the most common type of pancreatic lymphoma.
- Acute pancreatitis is an infrequent complication of pancreatic lymphoma.
Observation:
- A 42-year-old male presented with acute pancreatitis.
- Synchronous pancreatic and pulmonary involvement by non-Hodgkin's lymphoma was diagnosed.
- Imaging revealed pancreatic masses and a pulmonary infiltrate.
Findings:
- Fine-needle aspiration biopsy confirmed diffuse large B-cell lymphoma in both the pancreas and lungs.
- The patient was staged as IV-A with low-intermediate risk.
- The patient received six cycles of chemotherapy.
Implications:
- This is the first reported case of DLBCL with concurrent primary pancreatic and pulmonary involvement.
- Highlights the importance of histopathological diagnosis for pancreatic masses to differentiate lymphoma from other conditions.
- Underscores that pancreatic lymphoma can be a rare cause of acute pancreatitis.
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