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Related Experiment Video

Updated: May 26, 2026

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

Published on: September 18, 2014

Mastication suppresses initial gastric emptying by modulating gastric activity.

H Ohmure¹, H Takada, K Nagayama

¹Kagoshima University Graduate School of Medical and Dental Sciences, Department of Orthodontics, 8-35-1, Sakuragaoka, Kagoshima 890-8544, Japan.

Journal of Dental Research

|December 30, 2011

Summary

Chewing gum suppressed gastric emptying and reduced gastric electrical activity in healthy men. This suggests mastication inhibits initial gastric function, impacting digestion.

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Gastrointestinal Motility Monitor (GIMM)

Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

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Last Updated: May 26, 2026

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

Published on: September 18, 2014

Gastrointestinal Motility Monitor (GIMM)

Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

Area of Science:

Gastroenterology
Physiology

Background:

Mastication influences gastric activity, but its precise role in gastric emptying and motility remains unclear.
Previous research has not fully isolated the effects of mastication from factors like food texture, taste, and smell.

Purpose of the Study:

To investigate the direct impact of mastication on gastric emptying and gastric myoelectrical activity.
To elucidate the functional relationship between mastication and gastric function, excluding confounding variables.

Main Methods:

A randomized trial involving 14 healthy men.
Utilized a (13)C-acetate breath test, electrogastrography, and electrocardiography.
Assessed autonomic nerve activity via heart rate variability analysis, comparing ingestion with and without gum chewing.

Main Results:

Gastric emptying was significantly delayed in the group that engaged in mastication (gum chewing).
Gastric myoelectrical activity was suppressed during mastication and gradually recovered afterward.
A decrease in heart rate variability's high-frequency power correlated with gastric electrical activity suppression.

Conclusions:

Mastication directly suppresses initial gastric emptying.
This suppression is attributed to mastication-induced inhibition of gastric activity.
The findings highlight a neural inhibitory pathway linking mastication to gastric function.