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Mastication suppresses initial gastric emptying by modulating gastric activity.
H Ohmure1, H Takada, K Nagayama
1Kagoshima University Graduate School of Medical and Dental Sciences, Department of Orthodontics, 8-35-1, Sakuragaoka, Kagoshima 890-8544, Japan.
Journal of Dental Research
|December 30, 2011
Summary
Chewing gum suppressed gastric emptying and reduced gastric electrical activity in healthy men. This suggests mastication inhibits initial gastric function, impacting digestion.
Area of Science:
- Gastroenterology
- Physiology
Background:
- Mastication influences gastric activity, but its precise role in gastric emptying and motility remains unclear.
- Previous research has not fully isolated the effects of mastication from factors like food texture, taste, and smell.
Purpose of the Study:
- To investigate the direct impact of mastication on gastric emptying and gastric myoelectrical activity.
- To elucidate the functional relationship between mastication and gastric function, excluding confounding variables.
Main Methods:
- A randomized trial involving 14 healthy men.
- Utilized a (13)C-acetate breath test, electrogastrography, and electrocardiography.
- Assessed autonomic nerve activity via heart rate variability analysis, comparing ingestion with and without gum chewing.
Main Results:
- Gastric emptying was significantly delayed in the group that engaged in mastication (gum chewing).
- Gastric myoelectrical activity was suppressed during mastication and gradually recovered afterward.
- A decrease in heart rate variability's high-frequency power correlated with gastric electrical activity suppression.
Conclusions:
- Mastication directly suppresses initial gastric emptying.
- This suppression is attributed to mastication-induced inhibition of gastric activity.
- The findings highlight a neural inhibitory pathway linking mastication to gastric function.
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