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Updated: May 26, 2026

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Published on: September 5, 2025
Endoscopic therapy in chronic pancreatitis.
Damien Meng Yew Tan1, Stuart Sherman
1Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore. damien.tan.m.y@sgh.com.sg
Endoscopic therapy offers effective management for chronic pancreatitis (CP) complications, including duct obstruction, leaks, and pseudocysts. It also provides pain relief via endoscopic ultrasound-guided celiac plexus block, improving patient quality of life.
Area of Science:
- Gastroenterology
- Interventional Endoscopy
Background:
- Chronic pancreatitis (CP) is a severe condition causing persistent abdominal pain and malnutrition.
- Treatment aims to manage symptoms, halt disease progression, and address complications.
Purpose of the Study:
- To review the role of endoscopic therapy in managing chronic pancreatitis.
- To explore endoscopic interventions for pancreatic duct obstruction, leaks, pseudocysts, and pain management.
Main Methods:
- Literature review focusing on endoscopic interventions for CP.
- Analysis of endoscopic techniques for pancreatic duct and bile duct issues.
- Evaluation of endoscopic ultrasound-guided celiac plexus block for pain relief.
Main Results:
- Endoscopic therapy is crucial for selected CP patients, especially when medical or surgical options are limited.
- Interventions include relieving pancreatic duct (PD) and bile duct obstruction, closing PD leaks, and draining pseudocysts.
- Endoscopic ultrasound-guided celiac plexus block shows potential for pain management in CP.
Conclusions:
- Endoscopic therapy is a vital component of a multidisciplinary approach to chronic pancreatitis.
- It provides effective solutions for specific CP complications and pain.
- Further research may enhance the role of endoscopic interventions in CP management.
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