Related Experiment Video
Updated: May 26, 2026

Lipopolysaccharide Infusion as a Porcine Endotoxemic Shock Model
Published on: December 8, 2023
Influenza A/H1N1 septic shock in a patient with systemic lupus erythematosus. A case report
Konstantinos Tselios1, Ritsa Tsioka, Alexandros Sarantopoulos
1Clinical Immunology Unit, 2nd Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Background:
Immunocompromised patients, such as systemic lupus erythematosus (SLE) sufferers have an increased risk of mortality, following influenza infection. In the recent pandemic, influenza A H1NI virus caused 18449 deaths, mainly because of adult respiratory distress syndrome or bacterial co-infections.
Case Presentation:
In this case report, an SLE patient with viral-induced septic shock, without overt pulmonary involvement, is discussed. The patient was administered oseltamivir and supportive treatment, including wide-spectrum antibiotics, vasopressors and steroids, according to the guidelines proposed for bacterial sepsis and septic shock. She finally survived and experienced a lupus flare soon after intensive care unit (ICU) discharge.
Conclusions:
To our knowledge, this is the first case to report severe septic shock from influenza A/H1N1 virus, without overt pulmonary involvement.
Related Concept Videos
Acute Inflammation III: Local and Systemic Effects
Nephrotic Syndrome II : Assessment and Medical Management
Influenza
Rheumatic Heart Disease IV: Nursing Management
Nephrotic Syndrome III : Nursing Management
Nephrotic Syndrome I : Introduction