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Updated: May 26, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
Published on: September 8, 2023
Bone quality analysis using X-ray microtomography and microfluorescence
E Sales1, I Lima, J T de Assis
1Nuclear Instrumentation Laboratory, PEN/COPPE/UFRJ, PO Box: 68509, 21.941-972, Rio de Janeiro, Brazil.
Abstract:
Bone quality is an evaluation index often applied in order to interpret clinical observations made upon bone health, such as bone mineral density, micro and macro architecture, and mineral content. Conventional inspection techniques do not provide full information on trabecular bone quality. This study shows the high resolution potential and the non-destructive character of X-ray microtomography and microfluorescence upon the application of such techniques for evaluating bone quality. The mineral content assessment was performed by two-dimensional concentration mappings of calcium, zinc, and strontium. The results showed significant changes in bone morphology.

