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Ph chromosome in a patient with non-leukemic non-Hodgkin B-cell lymphoma
1Third Department of Internal Medicine, Kyoto First Red Cross Hospital, Japan.
American Journal of Hematology
|November 1, 1990
Abstract:
A standard Philadelphia translocation, t(9;22) (q34;q11), was found in lymph node cells from a patient with non-leukemic non-Hodgkin lymphoma at the time of diagnosis. The rearrangement of the breakpoint cluster region (bcr) was not detected with a bcr-3' probe. The neoplastic clone was of monoclonal B-cell character with E-, CD5-, CD10-, CD13-, CD19+, CD20+, CD21+, CD25-, HLA DR+, and positive surface Ig(kappa). The patient showed no evidence of chronic myelogenous leukemia.