Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However, frequent irregular...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anthocyanins.

Advances in nutrition (Bethesda, Md.)·2026
Same author

Serum Magnesium Concentrations in the United States-An Updated Population Reference Interval in Children and Adults.

The Journal of nutrition·2026
Same author

Effect of eggs on Maya child development and growth: the Saqmolo' Project randomized clinical trial.

Lancet regional health. Americas·2026
Same author

Accelerating the pace and accuracy of systematic reviews using AI: a validation study.

Systematic reviews·2025
Same author

Implementation of the nutrition care process on mortality risk in critically ill COVID-19 patients - a registry longitudinal cohort study.

Annals of medicine·2025
Same author

Magnesium Depletion Score as an Indicator of Health Risk and Nutritional Status-A Scoping Review.

Nutrients·2025

Related Experiment Video

Updated: May 26, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
12:00

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro

Published on: July 5, 2017

Anthocyanins in cardiovascular disease.

Taylor C Wallace1

  • 1Developing Solutions, LLC, Washington, DC 20008, USA. taylor.wallace@me.com

Advances in Nutrition (Bethesda, Md.)
|January 3, 2012
PubMed
Summary

Anthocyanins, natural plant pigments, show promise in preventing cardiovascular disease (CVD) by regulating signaling pathways. Further research is needed to understand their absorption and metabolism for effective CVD prevention.

Area of Science:

  • Nutritional Science
  • Biochemistry
  • Food Science

Background:

  • Anthocyanins are abundant plant flavonoids responsible for red-orange to blue-violet colors in foods.
  • Their consumption is higher than other flavonoids, with growing use as natural food colorants.
  • Emerging evidence links anthocyanin intake to health benefits, particularly cardiovascular disease (CVD) prevention.

Purpose of the Study:

  • To review the latest research on anthocyanin bioavailability, bioactivity, and CVD preventative effects.
  • To summarize proposed mechanisms of action for anthocyanins in CVD prevention.
  • To present findings from in vitro, in vivo, epidemiological, and clinical studies.

Main Methods:

  • Review of peer-reviewed publications over the past two decades.

More Related Videos

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
07:40

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy

Published on: May 26, 2023

Alternative Methods for the Detection of Superoxide Anion Generation in Platelets
06:35

Alternative Methods for the Detection of Superoxide Anion Generation in Platelets

Published on: March 29, 2024

Related Experiment Videos

Last Updated: May 26, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
12:00

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro

Published on: July 5, 2017

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
07:40

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy

Published on: May 26, 2023

Alternative Methods for the Detection of Superoxide Anion Generation in Platelets
06:35

Alternative Methods for the Detection of Superoxide Anion Generation in Platelets

Published on: March 29, 2024

  • Analysis of in vitro cell culture and in vivo animal model studies.
  • Inclusion of epidemiological data and human clinical trial results.

    • Main Results:

    • Anthocyanins possess in vitro antioxidant activity and may modulate signaling pathways relevant to CVD.
    • Synergistic effects with other phytochemicals complicate individual component analysis.
    • In vitro and in vivo studies suggest potential CVD preventative mechanisms.

    Conclusions:

    • Anthocyanins show promise for CVD prevention through various mechanisms.
    • Limited but encouraging human data exists.
    • Further research on anthocyanin absorption and metabolism is crucial for evaluating their role in CVD prevention.