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Related Concept Videos

Cranial Nerves: Types Part I01:14

Cranial Nerves: Types Part I

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
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The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
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The sympathetic chain ganglia, also known as the sympathetic trunk ganglia or paravertebral ganglia, are a series of ganglia located bilaterally on either side of the spinal column. These ganglia serve as relay stations for the sympathetic nervous system. Preganglionic neurons originating in the spinal cord project their axons to the sympathetic chain ganglia. Within the ganglia, these preganglionic fibers synapse with postganglionic neurons.The postganglionic neurons of the sympathetic trunk...
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Related Experiment Video

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In-Vivo Calcium Imaging of Sensory Neurons in the Rat Trigeminal Ganglion
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Peripheral painful traumatic trigeminal neuropathies.

R Benoliel1, J Kahn, E Eliav

  • 1Department of Oral Medicine, The Faculty of Dentistry, Hebrew University-Hadassah, Jerusalem, Israel. benoliel@cc.huji.ac.il

Oral Diseases
|January 4, 2012
PubMed
Summary

This review introduces peripheral painful traumatic trigeminal neuropathy (PPTTN) to describe trigeminal nerve pain from trauma. It proposes a treatment algorithm for this challenging condition, offering a new perspective on its pathophysiology.

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Area of Science:

  • Neurology
  • Pain Medicine
  • Trauma Surgery

Background:

  • Traumatic injuries can cause persistent trigeminal nerve pain.
  • Current understanding of this condition is limited, hindering effective treatment.
  • A precise definition and classification are needed for better patient management.

Purpose of the Study:

  • To review the clinical, pathophysiological, and therapeutic aspects of traumatically induced trigeminal nerve pain.
  • To propose a new, more accurate terminology: peripheral painful traumatic trigeminal neuropathy (PPTTN).
  • To present a treatment algorithm for traumatic trigeminal neuropathies.

Main Methods:

  • Comprehensive literature review of clinical presentations, pathophysiology, and treatments.
  • Analysis of existing studies on trigeminal and spinal nerve injury models.
  • Development of a treatment algorithm based on literature evidence.

Main Results:

  • Traumatic trigeminal nerve pain is complex with unique pathophysiological aspects compared to other neuropathies.
  • Existing treatment strategies for neuropathic pain have variable efficacy and side effect profiles.
  • A novel classification, PPTTN, is proposed for this patient group.

Conclusions:

  • Peripheral painful traumatic trigeminal neuropathy (PPTTN) offers a more accurate description of the condition.
  • Effective treatment for PPTTN is challenging, often with a poor prognosis.
  • The proposed treatment algorithm provides a structured approach to managing traumatic trigeminal neuropathies.