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Brain and liver dolichol in chronic alcoholism: a necropsy study
J J Kril1, R K Pullarkat, P S Pullarkat
1Department of Pathology, University of Sydney, Australia.
Alcoholism, Clinical and Experimental Research
|August 1, 1990
Abstract:
Cerebral gray and white matter and liver dolichol levels were measured in postmortem samples from chronic alcoholics and nonalcoholic controls following recent suggestions that dolichol levels may be used as a marker for alcoholism. No significant differences in brain dolichol were found between the control and alcoholic groups. A significant reduction in the liver dolichol was observed in the alcoholic group. This was most marked in those alcoholics with liver disease.