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Updated: May 26, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
[What is the burden associated with bipolar depression?]
1AP-HP, groupe hospitalier Henri Mondor, pôle de psychiatrie, Créteil, France. bruno.etain@inserm.fr
Abstract:
Intensity and frequency of the thymic symptoms are specific of the clinical picture of bipolar disorder patients. International classifications, don't take into account polarity as an operational criteria. Despite the lack of a consensual definition of polarity, close to 2/3 of the patients can be considered as having a predominant depressive form. Polarity can be considered as idiosyncratic of a patient and could be the preferential mode of evolution. Identification of the polarity of the disorder has interests in terms of prognosis and choice of treatment.
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