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Related Experiment Video

Updated: May 26, 2026

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults
05:26

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults

Published on: October 25, 2024

Cognitive dysfunction in cirrhosis is associated with falls: a prospective study.

Germán Soriano1, Eva Román, Joan Córdoba

  • 1Department of Gastroenterology, Institut d'Investigació Biomèdica Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. gsoriano@santpau.cat

Hepatology (Baltimore, Md.)
|January 4, 2012
PubMed
Summary

Patients with cirrhosis and cognitive dysfunction (CD) are at high risk for falls. The Psychometric Hepatic Encephalopathy Score (PHES) effectively identifies these at-risk individuals, enabling targeted fall prevention strategies.

Related Experiment Videos

Last Updated: May 26, 2026

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults
05:26

Using Motion Capture Technology in the Instrumented Timed Up and Go Test to Detect the Risk of Falling in Aged Adults

Published on: October 25, 2024

Area of Science:

  • Hepatology
  • Neurology
  • Geriatrics

Background:

  • Falls are a significant concern for patients with debilitating conditions like cirrhosis.
  • Mild cognitive disturbances in cirrhosis patients may elevate fall risk.
  • Early identification of at-risk individuals is crucial for implementing preventive measures.

Purpose of the Study:

  • To evaluate the predictive capability of the Psychometric Hepatic Encephalopathy Score (PHES) in identifying cirrhosis patients prone to falls.
  • To assess the association between cognitive dysfunction (CD) and fall incidence in cirrhosis.
  • To determine the clinical impact of falls in cirrhosis patients with and without CD.

Main Methods:

  • 122 outpatients with cirrhosis were assessed using the PHES.
  • Patients were categorized based on PHES scores indicating cognitive dysfunction (CD) (PHES < -4).
  • Follow-up assessments tracked fall incidence, fractures, and healthcare utilization.

Main Results:

  • 40.4% of patients with CD experienced falls, compared to 6.2% without CD (P < 0.001).
  • Fractures occurred in 9.5% of patients with CD versus 0% without (P = 0.01).
  • Patients with CD showed significantly higher rates of healthcare, emergency room, and hospital utilization due to falls.

Conclusions:

  • An abnormal PHES score is a strong predictor of fall risk in cirrhosis patients.
  • The PHES test can aid in raising awareness and identifying patients who would benefit from fall prevention strategies.
  • Cognitive dysfunction is an independent predictor of falls in this population.