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Related Experiment Videos

Human auditory steady-state response during general anesthesia.

G Plourde1, T W Picton

  • 1Human Neurosciences Research Unit, University of Ottawa, Ontario, Canada.

Anesthesia and Analgesia
|November 1, 1990
PubMed
Summary
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The 40-Hz auditory steady-state evoked response (ASSR) reliably tracks consciousness levels during anesthesia. ASSR amplitude changes closely mirrored patient awareness, unlike EEG, which was affected by muscle artifacts.

Area of Science:

  • Neuroscience
  • Anesthesiology
  • Brain-computer interfaces

Background:

  • The 40-Hz auditory steady-state evoked response (ASSR) is a brain's electrical activity.
  • Assessing consciousness during anesthesia is critical for patient safety.

Purpose of the Study:

  • To evaluate the 40-Hz ASSR as a measure of consciousness level during anesthesia.
  • To compare ASSR with electroencephalogram (EEG) for reliability.

Main Methods:

  • 10 surgical patients undergoing anesthesia with thiopental, fentanyl, and isoflurane.
  • ASSR and EEG recorded during pre-induction, induction, anesthesia, emergence, and recovery.
  • Auditory stimulus detection task used to measure consciousness level.

Main Results:

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  • ASSR amplitude significantly decreased during induction and anesthesia, then increased during emergence and recovery.
  • ASSR changes paralleled the level of consciousness.
  • EEG measurements were confounded by muscle artifacts during emergence and recovery.

Conclusions:

  • The 40-Hz ASSR amplitude is a reliable indicator of consciousness level during anesthesia.
  • ASSR offers a more dependable measure of consciousness than EEG in this context.