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Biological properties of new viologen-phosphorus dendrimers
Karol Ciepluch1, Nadia Katir, Abdelkrim El Kadib
1Department of General Biophysics, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland.
Abstract:
Some biological properties of eight dendrimers incorporating both phosphorus linkages and viologen units within their cascade structure or at the periphery were investigated for the first time. In particular cytotoxicity, hemotoxicity, and antimicrobial and antifungal activity of these new macromolecules were examined. Even if for example all these species exhibited good antimicrobial properties, it was demonstrated that their behavior strongly depends on several parameters as their size and molecular weight, the number of viologen units and the nature of the terminal groups.
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