Related Experiment Video
Updated: May 26, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Oral intake 6 months after acute ischemic stroke
Makoto Nakajima1, Yuichiro Inatomi, Toshiro Yonehara
1Department of Neurology, Stroke Center, Saiseikai Kumamoto Hospital, Japan. nakazima04@gmail.com
Internal Medicine (Tokyo, Japan)
|January 5, 2012
Summary
Predicting oral intake after stroke is crucial. Patients independent before stroke and showing improved National Institutes of Health Stroke Scale (NIHSS) scores by day 10 are likely to regain oral intake within 6 months.
Area of Science:
- Neurology
- Gastroenterology
Background:
- Percutaneous endoscopic gastrostomy (PEG) placement in acute stroke patients is common, but criteria for its necessity and timing remain unclear.
- Identifying predictors for oral intake can optimize patient management and prevent unnecessary procedures.
Purpose of the Study:
- To identify predictors of oral intake 6 months after acute ischemic stroke onset.
- To inform clinical decision-making regarding PEG placement in stroke survivors.
Main Methods:
- A prospective database of 738 acute ischemic stroke patients was analyzed.
- Patients surviving 6 months and responding to a questionnaire were categorized by oral intake status.
- Multivariate analysis identified independent predictors for oral intake.
Main Results:
- Of 525 eligible patients, 92.4% achieved oral intake at 6 months.
- Pre-stroke modified Rankin Scale score of 0 (OR 2.70) and National Institutes of Health Stroke Scale (NIHSS) score ≤9 on day 10 (OR 21.12) were significant predictors.
- Admission NIHSS score was not a predictor of 6-month oral intake.
Conclusions:
- Stroke patients who were independent before stroke and show decreasing NIHSS scores by day 10 have a high likelihood of regaining oral function.
- Caution is advised regarding early PEG placement in these patients, as swallowing function may improve spontaneously.
Related Concept Videos
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:15Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
01:17Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
01:26Transient Ischemic Attack l: Introduction
A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...