Gd-DTPA-based MR-visible polymer for direct visualization of interventional devices
Tomoka Kurita1, Kagayaki Kuroda, Takeo Ohsaka
1Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yokohama, Japan. tomoka_kurita@terumo.co.jp
Abstract:
We developed a Gd-DTPA (gadolinium(III)-diethylenetriaminepentaacetic acid)-based coating copolymer of hydrophilic and hydrophobic subunits to obtain visibility, hydrophilicity, and durability for passive visualization of catheters used in MR-guided interventions. We then examined a metal-free catheter coated with the polymer in a phantom and in porcine brain tissue ex vivo. Successful visualization of the coated device demonstrated the applicability of the new coating technique for visualizing catheters used in MR-guided interventions.
