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Updated: May 26, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Extracardiac findings detected by cardiac magnetic resonance imaging
Rolf Wyttenbach1, Nathalie Médioni, Paolo Santini
1Department of Radiology, Ospedale San Giovanni Bellinzona (EOC), CH-6500 Bellinzona, Switzerland. rolf.wyttenbach@bluewin.ch
Insights
A second review of cardiac MRI scans revealed significantly more extracardiac findings (ECF) than the initial reading. This highlights the importance of thoroughly examining all cardiac MRI sequences for potentially significant ECF.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Diagnostic Medicine
Background:
- Cardiac Magnetic Resonance (CMR) is a key imaging modality for cardiac assessment.
- Incidental extracardiac findings (ECF) are common but may be overlooked in standard cardiac-focused reviews.
- The clinical significance and detection rates of ECF during CMR warrant further investigation.
Purpose of the Study:
- To determine the prevalence and clinical importance of ECF in patients undergoing CMR.
- To evaluate whether a standard cardiac-focused CMR reading underestimates the detection of ECF.
- To test the hypothesis that a dedicated second reading improves ECF detection.
Main Methods:
- A retrospective review of 401 consecutive CMR studies (1.5 T) was performed.
- Indications included ischemic heart disease and cardiomyopathy.
- A second, dedicated review by the same radiologist focused on identifying all ECF, including scout images, and compared findings with the initial clinical reading.
Main Results:
- 250 incidental ECF were detected across all studies.
- 84 ECF (34% of incidental findings) were deemed potentially significant, requiring further work-up.
- The second dedicated reading identified significantly more ECF (both significant and non-significant) compared to the initial clinical reading (P < 0.00001).
Conclusions:
- Approximately one-fifth of patients undergoing CMR have potentially significant ECF requiring additional investigation.
- A dedicated, comprehensive review of CMR sequences, including scout images, significantly increases the detection of ECF.
- Radiologists should actively search for ECF during CMR interpretation to ensure comprehensive patient assessment.
Objective:
To determine the prevalence and importance of extracardiac findings (ECF) in patients undergoing clinical CMR and to test the hypothesis that the original CMR reading focusing on the heart may underestimate extracardiac abnormalities.
Methods:
401 consecutive patients (mean age 53 years) underwent CMR at 1.5 T. Main indications were ischaemic heart disease (n = 183) and cardiomyopathy (n = 164). All CMR sequences, including scout images, were reviewed with specific attention to ECF in a second reading by the same radiologist who performed the first clinical reading. Potentially significant findings were defined as abnormalities requiring additional clinical or radiological follow-up.
Results:
250 incidental ECF were detected, of which 84 (34%) had potentially significant ECF including bronchial carcinoma (n = 1), lung consolidation (n = 7) and abdominal abnormalities. In 166 CMR studies (41%) non-significant ECF were detected. The number of ECF identified at second versus first reading was higher for significant (84 vs. 47) and non-significant (166 vs. 36) findings (P < 0.00001).
Conclusions:
About one fifth of patients undergoing CMR were found to have potentially significant ECF requiring additional work-up. The second dedicated reading detected significantly more ECF compared with the first clinical reading emphasising the importance of active search for extracardiac abnormalities when evaluating CMR studies.
Key Points:
• Many patients undergoing cardiac MR have significant extracardiac findings (ECF) • These impact on management and require additional work-up. • Wide review of scout and cine sequences will detect most ECFs. • Education of radiologists is important to identify ECFs on CMR studies.
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