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Related Concept Videos

Gene-Environment Interactions01:20

Gene-Environment Interactions

Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
Causes of Social Behavior III: Biological and Environmental Influences01:28

Causes of Social Behavior III: Biological and Environmental Influences

Social behavior is a complex phenomenon that arises from the interaction between biological predispositions and environmental influences. This intricate interplay shapes how individuals think, feel, and act in various social contexts. Understanding these mechanisms requires insights from psychology, neuroscience, genetics, and evolutionary theory.Environmental Influences on Social BehaviorEnvironmental factors, including temperature, odors, and visual stimuli, play a crucial role in shaping...

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Related Experiment Video

Updated: May 26, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
13:11

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain

Published on: July 12, 2012

Epigenetics and the environment: emerging patterns and implications.

Robert Feil1, Mario F Fraga

  • 1Institute of Molecular Genetics (IGMM), CNRS UMR-5535 and University of Montpellier, 1919 route de Mende, 34293 Montpellier, France. robert.feil@igmm. cnrs.fr

Nature Reviews. Genetics
|January 5, 2012
PubMed
Summary
This summary is machine-generated.

Environmental factors like pollutants and stress can alter epigenetic modifications (DNA methylation, chromatin changes) in animals and plants. These changes can affect gene expression, development, and health across generations.

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Last Updated: May 26, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
13:11

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Published on: July 12, 2012

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Published on: October 8, 2017

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Area of Science:

  • Epigenetics
  • Environmental Science
  • Molecular Biology

Background:

  • Epigenetic phenomena, including DNA methylation and chromatin modifications, are crucial in animals and plants.
  • Environmental factors are increasingly recognized for their potential to influence these epigenetic processes.

Purpose of the Study:

  • To explore how environmental factors modulate the establishment and maintenance of epigenetic modifications.
  • To understand the link between environmental influences, gene expression, and phenotypic outcomes.

Main Methods:

  • Review of existing literature on environmental impacts on epigenetics.
  • Analysis of experimental model systems to elucidate underlying mechanisms.

Main Results:

  • Environmental factors (chemical pollutants, diet, temperature) can induce long-lasting epigenetic changes.
  • These alterations can affect development, metabolism, and health, with potential transgenerational effects.

Conclusions:

  • Environmental modulation of epigenetics has significant implications for understanding development and disease.
  • Further research in model systems is vital for uncovering human-specific mechanisms.