Replication, gene expression and particle production by a consensus Merkel Cell Polyomavirus (MCPyV) genome

Friederike Neumann1, Sophie Borchert, Claudia Schmidt

  • 1Institute for Microbiology and Virology, University Medical Center Eppendorf, Hamburg, Germany.

Plos One
|January 5, 2012
PubMed
Summary

Researchers created a synthetic Merkel cell polyomavirus (MCPyV) genome for in vitro studies. This system enables the study of viral replication and gene expression in human cell lines, aiding MCC pathogenesis research.

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