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Related Experiment Video

Updated: May 26, 2026

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model
06:14

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Published on: February 17, 2023

Perilous periodontitis: a clinical study.

Roby V Emmanuel1, Shiba Neelakantan

  • 1People's College of Dental Sciences and Research Centre, Bhopal.

The Practising Midwife
|January 6, 2012
PubMed
Summary

Periodontitis, a gum disease, may increase the risk of preterm low birth weight in infants. This study compared oral health in mothers with normal and low birth weight babies, finding a link between poor periodontal health and adverse birth outcomes.

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Area of Science:

  • Obstetrics and Gynecology
  • Periodontology
  • Public Health

Background:

  • Preterm low birth weight (PLBW) is a significant global health concern.
  • Maternal oral health, particularly periodontitis, is increasingly investigated for its potential impact on pregnancy outcomes.

Purpose of the Study:

  • To investigate if periodontitis in pregnant women is a risk factor for preterm low birth weight.
  • To compare the oral hygiene and periodontal status of mothers with normal birth weight infants versus those with PLBW infants.

Main Methods:

  • Assessed oral hygiene status using the Oral Hygiene Index-simplified (OHI-S).
  • Evaluated periodontal health via gingival bleeding index (GBI), probing pocket depth, and Community Periodontal Index of Treatment Needs (CPITN).
  • Compared clinical parameters between mothers of normal birth weight infants (Group A) and mothers of PLBW infants (Group B).

Main Results:

  • Mothers of preterm low birth weight infants exhibited poorer oral hygiene and periodontal status compared to mothers of normal birth weight infants.
  • Specific clinical parameters like GBI and probing pocket depth were significantly different between the groups (details in full article).

Conclusions:

  • Poor periodontal condition in pregnant women may be a significant risk factor for preterm low birth weight.
  • Effective periodontal treatment and improved oral hygiene during pregnancy could potentially mitigate the risk of PLBW.

Related Experiment Videos

Last Updated: May 26, 2026

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model
06:14

Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

Published on: February 17, 2023