Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Driving performance of outpatients achieving discharge criteria after deep sedation is worse than these of their escort-driver: a prospective observational study on simulator.

Acta gastro-enterologica Belgica·2023
Same author

[Interscalene block and shoulder surgery. Literature review and new method of infiltration].

Revue medicale de Liege·2021
Same author

[Treatment of post-total knee replacement gonalgy by radiofrequency ablation of the genicular nerves].

Revue medicale de Liege·2021
Same author

[Predictive scores used during the anesthetic preoperative visit. Part 2. Assessment of perioperative risk].

Revue medicale de Liege·2021
Same author

[Predictive scores used during the anesthetic preoperative visit. Part 1. Assessment of postoperative complications].

Revue medicale de Liege·2021
Same author

[Spontaneous rupture of a splenic artery aneurysm during the third trimester of pregnancy].

Revue medicale de Liege·2021

Related Experiment Video

Updated: May 26, 2026

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

[Post-dural puncture headache: treatment and prevention].

L Lenelle1, B Lahaye-Goffart, P Y Dewandre

  • 1Département d'Anesthésie-Réanimation, C.H.U. de Liège, Belgique.

Revue Medicale De Liege
|January 6, 2012
PubMed
Summary

Post-dural puncture headache (PDPH) is a common complication following intentional or accidental dural puncture. While the epidural blood patch shows benefits, standardized prevention and treatment for PDPH remain elusive.

More Related Videos

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
09:01

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Published on: October 15, 2021

Related Experiment Videos

Last Updated: May 26, 2026

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
05:40

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
09:01

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Published on: October 15, 2021

Area of Science:

  • Anesthesiology
  • Neurology
  • Obstetrics

Context:

  • Post-dural puncture headache (PDPH) is a frequent complication of dural puncture procedures, impacting patient recovery.
  • Dural punctures occur intentionally (e.g., spinal blocks) or accidentally (e.g., epidural blocks), with obstetric patients being particularly susceptible.
  • Current management strategies for PDPH lack standardization, affecting patient outcomes.

Purpose:

  • To review the current understanding of post-dural puncture headache (PDPH), including its causes, risk factors, and management.
  • To highlight the efficacy of the epidural blood patch as a treatment option.
  • To discuss the limitations in current preventative measures for PDPH.

Summary:

  • PDPH is a significant iatrogenic complication following dural puncture, often incapacitating patients.
  • Risk factors are known, with obstetric patients facing a higher incidence.
  • While the epidural blood patch demonstrates therapeutic benefits, standardized treatment and proven preventative strategies for PDPH are still lacking.

Impact:

  • Informs clinical practice regarding PDPH management and highlights areas for future research.
  • Emphasizes the need for standardized protocols for PDPH prevention and treatment.
  • Contributes to improved patient care and outcomes in procedures involving dural puncture.