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Published on: July 21, 2023
Recurrent congenital fibrosarcoma with heart metastases
Olli Lohi1, Martine Vornanen, Marketta Kähkönen
1Department of Pediatrics and Pediatric Research Centre, University of Tampere Medical School and Tampere University Hospital, Tampere, Finland. olli.lohi@uta.fi
Insights
Congenital fibrosarcoma, a rare infant cancer, can recur locally. This case highlights a rare instance of metastasis to the heart, successfully treated with chemotherapy, leading to a 3-year remission.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
- Soft Tissue Tumors
Background:
- Congenital fibrosarcoma is a rare malignant soft tissue tumor in infants.
- Typically, it exhibits local recurrence but rarely metastasizes in this age group.
- Metastasis to the heart represents an exceptionally uncommon presentation.
Abstract:
Congenital fibrosarcomas are malignant tumors that arise in soft tissues. In infants this unique tumor does not commonly metastasize, even though there may be local recurrences. We report here a boy who had congenital fibrosarcoma in his right foot, which was completely excised at the age of 3 days. Four months later, a solitary encapsulated metastasis emerged in thoracic chest wall, which was operated. During adjuvant chemotherapy he developed histologically confirmed fibrosarcoma metastases in the heart. After extended treatment with cyclophosphamide/topotecan and gemcitabine/docetaxel, the heart tumors disappeared and he has been in complete remission for 3 years.
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