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Updated: May 26, 2026

Intracellular Refolding Assay
Published on: January 24, 2012
Heat shock proteins (HSP): dermatological implications and perspectives
Wagner Vidal Magalhães1, Marcelo Fábio Gouveia Nogueira, Telma Mary Kaneko
1Laboratório de Controle Biológico de Qualidade de Medicamentos e Cosméticos - Universidade de São Paulo, Av. Prof. Lineu Prestes 580, Bloco 13, São Paulo, Brasil. wmagalhaes@usp.br
Abstract:
In recent years, several studies have demonstrated the protective effect of Heat Shock Proteins (HSP) on different organs and tissues under stressful conditions. However, most research explores the performance of those molecular chaperones during immune responses or pathological conditions like cancer, whereas the number of studies related to the performance of HSPs in the skin during diverse natural or physiopathological conditions is very low. Therefore, the aim of this article was to summarize the main concepts concerning the expression and performance of HSPs, from analysis of current medicine and cosmetics publications, as well as exploring the importance of these proteins in the dermatological area in physiological events such as cutaneous aging, skin cancer and wound healing and to present final considerations related to biotechnology performance in this area.
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