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Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...

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[Modern radiotherapy after breast-conserving surgery].

Csaba Polgár1, Tibor Major, János Fodor

  • 1Országos Onkológiai Intézet Budapest Ráth Gy. u. 7-9. 1122. polgar@oncol.hu

Orvosi Hetilap
|January 6, 2012
PubMed
Summary

Breast-conserving surgery with whole breast irradiation is standard for early breast cancer. Research now focuses on risk-adapted radiotherapy, including accelerated partial breast irradiation and omitting radiation for select patients.

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Area of Science:

  • Oncology
  • Radiotherapy
  • Surgical Oncology

Context:

  • Breast-conserving surgery (BCS) followed by whole breast irradiation (WBI) is the standard for early-stage breast carcinoma.
  • Increased early-stage diagnoses due to screening necessitate personalized treatment approaches.
  • Evolving treatment paradigms aim to optimize radiotherapy for early breast cancer.

Purpose:

  • To review recent studies on individual risk-adapted radiotherapy after BCS for early breast carcinoma.
  • To explore the efficacy of accelerated partial breast irradiation (APBI) and WBI.
  • To identify patient subgroups who may safely omit radiotherapy post-BCS.

Summary:

  • The standard of care for early breast cancer has shifted towards risk-adapted radiotherapy protocols.
  • Accelerated breast irradiation techniques, including APBI, are being evaluated.
  • Molecular gene expression assays show promise in predicting local recurrence risk.
  • Research is exploring the omission of radiotherapy in select patient groups.

Impact:

  • Advances in radiotherapy aim to reduce treatment toxicity while maintaining local control.
  • Personalized medicine approaches, guided by prognostic markers, are transforming breast cancer management.
  • Optimizing radiotherapy selection improves outcomes for early-stage breast cancer patients.