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Multifocal Electroretinograms
Published on: December 4, 2011
Multifocal electroretinogram in normal emmetropic subjects: correlation with optical coherence tomography
Rajvardhan Azad1, Urmimala Ghatak, Yog Raj Sharma
1Dr. R. P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Indian Journal of Ophthalmology
|January 6, 2012
Summary
This study establishes a normative database for multifocal electroretinogram (mfERG) parameters in emmetropic individuals. No significant correlation was found between mfERG data and central macular thickness (CMT).
Area of Science:
- Ophthalmology
- Neuroscience
- Visual Science
Background:
- The multifocal electroretinogram (mfERG) assesses retinal function.
- Optical coherence tomography (OCT) measures retinal thickness.
- Establishing normative mfERG data is crucial for clinical interpretation.
Purpose of the Study:
- To create a normative database for mfERG parameters in healthy, emmetropic individuals.
- To investigate the correlation between mfERG responses and central macular thickness (CMT) measured by OCT.
Main Methods:
- mfERG responses (amplitude, implicit time of N1, P1, N2 waves) were recorded from 222 eyes of 111 emmetropic subjects.
- Data were analyzed across five eccentric retinal rings.
- Central macular thickness (CMT) was measured using OCT.
Main Results:
- A normative database for mfERG parameters was established.
- Amplitudes were highest in the fovea and decreased with eccentricity (P=0.0001).
- Latencies of P1 and N2 waves were longest centrally and shortened with eccentricity (P=0.0001).
Conclusions:
- Normative mfERG values for an emmetropic population have been successfully established.
- No statistically significant correlation was found between central macular thickness and mfERG parameters.
