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Updated: May 26, 2026

Synthesis and Exfoliation of Discotic Zirconium Phosphates to Obtain Colloidal Liquid Crystals
Published on: May 25, 2016
Zirconium phosphate nano-platelets: a novel platform for drug delivery in cancer therapy
Agustín Díaz1, Vipin Saxena, Julissa González
1Department of Chemistry, Texas A&M University, PO Box 30012, College Station, TX 77842-3012, USA. diaz@chem.tamu.edu
Abstract:
Doxorubicin was intercalated into novel zirconium phosphate nano-platelets (ZrP). The obtained doxorubicin intercalated ZrP nano-platelets had an impressive 34.9% (w/w) drug loading. We used this material to deliver doxorubicin to breast cancer cells (MCF-7). Cellular studies with MCF-7 cells showed higher uptake and cytotoxicity of doxorubicin loaded ZrP compared to free doxorubicin.
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