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Antibacterial effect, plasmid curing activity and chemical structure of some tricyclic compounds
Acta Microbiologica Academiae Scientiarum Hungaricae
|January 1, 1977
Abstract:
Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 microgram/ml. The antibacterial compounds deleted at 40-70% frequency the F'lac plasmid of Escherichia coli K12 LE-140.