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Improved cardiopulmonary exercise function after modified Nuss operation for pectus excavatum.

Mariann Tang¹, Hans Henrik Møller Nielsen, Maj Lesbo

¹Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery

|January 6, 2012

Summary

The Nuss procedure improved cardiac index and forced expiratory volume in 1 second (FEV(1)) in teenagers with pectus excavatum one year after surgery. However, cardiac function remained lower than in healthy controls.

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Area of Science:

Cardiology
Thoracic Surgery
Pediatric Medicine

Background:

Pectus excavatum can impair cardiac function during exercise.
The Nuss technique is a surgical repair for pectus excavatum.

Purpose of the Study:

To evaluate the impact of the Nuss procedure on cardiopulmonary function during exercise in teenagers with pectus excavatum.

Main Methods:

Compared 49 teenagers with pectus excavatum to 26 controls.
Assessed cardiac index, heart rate, VO(2) max, ventricular dimensions, and forced expiratory volume in 1 second (FEV(1)) at rest and during exercise before and one year after surgery.

Main Results:

Pre-surgery, patients had lower cardiac index and FEV(1) during exercise compared to controls.
One year post-Nuss surgery, patients showed significant improvements in cardiac index and FEV(1).
Despite improvements, patients' cardiac index remained lower than controls; VO(2) max increased in both groups, but more in controls.

Conclusions:

The Nuss operation improves cardiac index and FEV(1) in patients with pectus excavatum.
Cardiopulmonary function during exercise is still compromised post-surgery compared to healthy peers.