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De-novo histoid leprosy.
Srinivasa V Murthy1, Sudha M Rao, Thejaswini
1Department of Pathology, ESI-PGIMSR, Rajajinagar, Bangalore, India. srinipath@gmail.com
Histoid leprosy, a rare multibacillary leprosy variant, presents unique features and can mimic neurofibromatosis. This condition often arises in patients with dapsone resistance or relapse after treatment.
Area of Science:
- Dermatology
- Infectious Diseases
- Pathology
Background:
- Histoid leprosy is a rare variant of multibacillary leprosy.
- It is characterized by distinct clinical and histopathological findings.
- It is a subtype of lepromatous leprosy.
Observation:
- Histoid leprosy can occur in patients with dapsone resistance.
- It may arise in patients relapsing after dapsone monotherapy.
- The condition can also appear 'de-novo'.
Findings:
- The case presented clinically mimicked neurofibromatosis.
- Distinct clinical and histopathological features define histoid leprosy.
- This leprosy variant is associated with specific treatment outcomes.
Implications:
- Recognizing histoid leprosy is crucial for accurate diagnosis.
- Differentiating it from other conditions like neurofibromatosis is important for appropriate management.
- Understanding its occurrence in dapsone-resistant cases informs treatment strategies.
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