1,2-Dimeth-oxy-4-methyl-3-[(S)-p-tolyl-sulfin-yl]benzene

Virginia M Mastranzo1, José Luis Olivares, Rubén Sánchez-Obregón

  • 1Instituto de Química, UNAM, Circuito Exterior, Ciudad Universitaria, Delegación Coyoacán, CP 04510, México, DF, Mexico.

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Preparation and Reactions of Thiols02:33

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Thiols are prepared using the hydrosulfide anion as a nucleophile in a nucleophilic substitution reaction with alkyl halides. For instance, bromobutane reacts with sodium hydrosulfide to give butanethiol.
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Thiols and sulfides are sulfur analogs of alcohols and ethers, respectively, where the sulfur atom takes the place of the oxygen atom. Thus, thiols are generally represented as RSH, where R is an alkyl substituent and —SH is the functional group. On the other hand, in sulfides, the central sulfur atom is bonded to two hydrocarbon groups on either side. Depending upon the type of group, sulfides can be either symmetrical or asymmetrical. Both thiols and sulfides display a bent geometry, similar...
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